Mark Mitchell scored a career-high 25 points to lead No. 21 Missouri to an 82-58 rout of Oklahoma on Wednesday in Southeastern Conference action at Columbia, Mo.Mitchell’s performance pushed him past the 1,000-career point milestone.Caleb Grill scored 15 points, Tony Perkins added 12 and Anthony Robinson II chipped in 10 for the Tigers (18-6, 7-4 SEC), who improved to 16-1 at home this season.Duke Miles scored 18 points and Jalon Moore added 10 for the Sooners (16-8, 3-8), who lost their third straight game, all against ranked opponents.Missouri shot 54.2 percent from the floor and outscored Oklahoma 40-24 in the paint.Oklahoma stayed close early by claiming five early offensive rebounds and scoring its first eight points on second-chance opportunities.Missouri moved ahead 23-11 with a 14-3 run sparked by Jacob Crews’ transition 3-pointer.Jeremiah Fears steadied the Sooners by driving to the basket for a three-point play, but the Tigers answered by isolating Mitchell for attacks off the dribble.